Sepsis [top]

  • Pre-hepatic jaundice or hepatic jaundice
  • Fever, hypotension, tachycardia

Crigler-Najjar syndrome [top]

  • Hepatic jaundice
  • No elevation in LFTs on fasting

Gilbert's syndrome [top]

  • Hepatic jaundice
  • Hyperbilirubinaemia on fasting
  • No other LFT abnormalites, asymptomatic

Alcoholic hepatitis / cirrhosis [top]

  • Hepatic jaundice or obstructive jaundice
  • History of excessive alcohol consumption

Drug-induced jaundice [top]

  • Hepatic jaundice or obstructive jaundice
  • Hepatic: paracetamol, halothane
  • Obstructive: oral contraceptive pill, antibiotics etc.

Glandular fever [top]

  • Hepatic jaundice
  • Hepatomegaly, splenomegaly, lymphadenopathy
  • Sore throat, Malaise
  • Atypical lymphocytes

Viral hepatitis [top]

  • Hepatic jaundice
  • Hepatomegaly, right upper quadrantabdominal pain
  • Fever, vomiting
  • Hepatitis A: Faecal-oral spread
  • Hepatitis B, C: IVDU, blood transfusion, tattoos