Ulcerative colitis [top]

  • Recurrent diarrhoea with rectal bleeding
  • Lower abdominal pain
  • Fever, Raised inflammatory markers
  • Large joint polyarthritis, sacroilitis

Rheumatic fever [top]

  • Flitting polyarthritis, carditis
  • Recent streptococcal infection - scarlet fever or positive streptococcal serology
  • Erythema marginatum (annular erythema) or subcutaneous nodules
  • Sydenham's chorea
  • Fever, raised inflammatory markers

Reiter's syndrome [top]

  • Reactive arthritis manifesting asMonoarthritis or polyarthritis, urethritis, conjunctivitis
  • Preceding sexually transmitted infection (neisseria, chlamydia or intestinal infection (salmonela, shigella, campylobacter
  • Associated with circinate balanatis, keratoderma blennorrhagicum

Systemic lupus erythematosus [top]

  • Polyarthritis
  • Renal impairment, pleuritic chest pain
  • Rash, photosensitivity, alopecia
  • dsDNA+, ANA+

Rheumatoid arthritis [top]

  • Symmetrical deforming polyarthritis polyarthritis or monoarthritis Hand pain or deformity
  • Involvement of small joints of hands, wrists, knees knee pain
  • Morning stiffness
  • Can lead to severe deformities including swan-neck and boutonniere deformities
  • Usually RF+ve

Viral-induced arthritis [top]

  • Polyarthritis
  • History of rubella, EBV, mumps

Sjogren's syndrome [top]

  • Dry eyes xeropthalmia, Dry mouth xerostomia
  • May have associated polyarthritis
  • Serology: RF+, anti-Ro+, anti-La+

Chron's disease [top]

  • Recurrent diarrhoea with rectal bleeding
  • Central abdominal pain
  • Right lower quadrant mass
  • Weight loss, Mouth ulcers, Fistulae
  • Large joint polyarthritis, sacroilitis

Psoriatic arthritis [top]

  • May have other clinical features of psoriasis including nail pitting. Usually RF-ve.
  • Assymetric: Monoarthritis or oligoarthritis
  • Symmetrical deforming polyarthritis polyarthritis particularly distal interphalangeal joints hand pain or deformity
  • Rheumatoid-arthritis like
  • Arthritis mutilans
  • Ankylosing spondylitis-like

Psoriasitic arthritis [top]